Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart …
Chemokine-chemokine receptor interactions and the subsequent recruitment of T
lymphocytes to the graft are believed to be among the initial events in the development of
acute and chronic rejection of heart transplants. We sought to determine the role of
chemokine receptor Cxcr3 on the development of acute and chronic rejection in a multiple
minor Ag mismatched mouse heart transplant model. The frequencies and kinetics of
immunodominant H60 (LTFNYRNL) miHA-specific CD8 T cells in wild-type or Cxcr3 …
lymphocytes to the graft are believed to be among the initial events in the development of
acute and chronic rejection of heart transplants. We sought to determine the role of
chemokine receptor Cxcr3 on the development of acute and chronic rejection in a multiple
minor Ag mismatched mouse heart transplant model. The frequencies and kinetics of
immunodominant H60 (LTFNYRNL) miHA-specific CD8 T cells in wild-type or Cxcr3 …
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